Dosing & Level History
Enter date and time for each dose/level. Leave dose blank for levels only.
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1. DATE: Date of dose/level (YYYY-MM-DD)
2. TIME: Time of day (HH:MM, 24-hour)
3. DOSE: Amount in mg (leave blank for levels)
4. DURATION: Infusion time in hours (usually 1-2h)
5. LEVEL: Observed concentration (mg/L)
Individual Parameters
Population vs Individual
Event Summary (Hours from Reference)
AUC24 Steady State (mg·h/L)
Trough Steady State (mg/L)
Time to Steady State (h)
CrCL used (mL/min)
Parameter Summary
⚠️ Disclaimer
This application is intended for use by healthcare professionals as a decision support tool. It is not a substitute for clinical judgment. The authors assume no responsibility or liability for any errors or omissions in the content of this site. The information contained in this site is provided on an 'as is' basis with no guarantees of completeness, accuracy, usefulness or timeliness.
📚 Model References
- Goti et al: Hospitalized patients with and without hemodialysis have similar vancomycin clearance.' Ther Drug Monit. 2018.
- Thomson et al: Development and evaluation of vancomycin dosage guidelines designed to achieve new target concentrations.' J Antimicrob Chemother. 2009.
- Hughes JH et al: A hybrid machine learning/pharmacokinetic approach outperforms maximum a posteriori Bayesian estimation by selectively flattening model priors. CPT Pharmacometrics Syst Pharmacol. 2021
- Buelga et al: Population pharmacokinetic analysis of vancomycin in patients with hematological malignancies.' Antimicrob Agents Chemother. 2005.
- Hughes MS et al: Developing Parametric and Nonparametric Models for Model-Informed Precision Dosing: A Quality Improvement Effort in Vancomycin for Patients With Obesity. Ther Drug Monit. 2024
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Last Updated: January 2026 beta v0.70
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