Dosing & Level History
Enter date and time for each dose/level. Leave dose blank for levels only.
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1. DATE: Date of dose/level (YYYY-MM-DD)
2. TIME: Time of day (HH:MM, 24-hour)
3. DOSE: Amount in mg (leave blank for levels)
4. DURATION: Infusion time in hours (usually 1-2h)
5. LEVEL: Observed concentration (mg/L)
Population vs Individual
Event Summary (Hours from Reference)
AUC24 Steady State (mg·h/L)
Trough Steady State (mg/L)
Time to Steady State (h)
CrCL used (mL/min)
Parameter Summary
⚠️ Disclaimer
This application is currently under development and has not been validated for clinical use. It is provided for educational, research, and software evaluation purposes only. It must not be used as the sole basis for patient care, dosing decisions, or other clinical decision-making.
Outputs may be incomplete, inaccurate, or subject to change without notice. Use of this application does not replace independent verification, institutional protocols, or professional clinical judgment. The authors and contributors disclaim responsibility for errors, omissions, or consequences arising from use of this application.
📚 Model References
- Goti et al: Hospitalized patients with and without hemodialysis have similar vancomycin clearance.' Ther Drug Monit. 2018.
- Thomson et al: Development and evaluation of vancomycin dosage guidelines designed to achieve new target concentrations.' J Antimicrob Chemother. 2009.
- Hughes JH et al: A hybrid machine learning/pharmacokinetic approach outperforms maximum a posteriori Bayesian estimation by selectively flattening model priors. CPT Pharmacometrics Syst Pharmacol. 2021
- Buelga et al: Population pharmacokinetic analysis of vancomycin in patients with hematological malignancies.' Antimicrob Agents Chemother. 2005.
- Hughes MS et al: Developing Parametric and Nonparametric Models for Model-Informed Precision Dosing: A Quality Improvement Effort in Vancomycin for Patients With Obesity. Ther Drug Monit. 2024
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Last Updated: March 2026 beta v0.80
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